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Dealing with enterocutaneous fistulas at Evangel
published 26-11-2007

Views : 750

Times marked as favorite : 110


We now have four patients in the hospital who have a condition called enterocutaneous fistula. They all had surgery at other hospitals for various problems but developed a leak in their intestines so now they have stool leaking out their abdominal wounds or their vaginas. Most come to us very sick, dehydrated, severely malnourished and anemic and some near death.

Our approach in helping them is pretty simple; they need food – protein – so we put them on a regimented schedule of taking a soy bean and peanut formula called “kwash pap” because it is used to help malnourished children with kwashiorkor. It is remarkable how well most of these patients do after a few weeks of a high protein diet. Some actually close their fistulas spontaneously without need for surgery. At least they are in better shape to have the surgery so their outcome is better.

I feel so badly for these dear people who have suffered so much at the expense of other “healers” and how desperate they are. Several are from the other main religion so we pray for both spiritual and physical healing. Without the benefit of expensive intravenous nutritional support, we rely on simple foods and prayer.
--Dr. Bill Ardill, SIM Missionary and chief surgeon at Evangel
Keywords : fistula; enterocutaneous; nutrition; support; surgery; Africa; Nigeria
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Better first line treatment needed for children with severe pneumonia
published 13-11-2007

Views : 944

Times marked as favorite : 117


This Lancet article reports an important observational study from South Africa. The authors investigated 358 children aged 1–59 months, regardless of HIV status, who presented with WHO-defined severe or very severe pneumonia. Sixty-eight percent of the children were HIV infected. The empiric treatment used was benzylpenicillin, gentamicin and, for those less than a year old, high-dose trimethoprim-sulfamethoxazole.

FIndings included the fact that in the infants, 42% failed therapy by 48 hours and 6% subsequently. Many of those failing had polymicrobial infections (more than one organism). M. tuberculosis, S. aureus and, in infants, PCP were common among those failing treatment. The authors conclude that (in this HIV-prevalent area) existing empiric treatment recommendations for children with severe pneumonia are inadequate, since nearly half the children failed treatment.

Read more to see a table of organisms isolated from those failing treatment, then see the original article as well.

Keywords : pneumonia; HIV; infants; children; Africa; severe; antibiotics; treatment; empiric; journal club
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Haloperidol plus promethazine better than haloperidol alone for rapid tranquilization
published 24-10-2007

Views : 741

Times marked as favorite : 106


"Results Primary outcome data were available for 311 (98.4%) people, 77% of whom were thought to have a psychotic illness. Patients allocated haloperidol plus promethazine were more likely to be tranquil or asleep by 20 minutes than those who received intramuscular haloperidol alone (relative risk 1.30, 95% confidence interval 1.10 to 1.55; number needed to treat 6, 95% confidence interval 4 to 16; P=0.002). No differences were found after 20 minutes. However, 10 cases of acute dystonia occurred, all in the haloperidol alone group. "


Rapid tranquillisation in psychiatric emergency settings in Brazil: pragmatic randomised controlled trial of intramuscular haloperidol versus intramuscular haloperidol plus promethazine. BMJ, doi:10.1136/bmj.39339.448819.AE (published 22 October 2007)
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Hannah
published 05-11-2007

Views : 887

Times marked as favorite : 114


ImageThe two day old baby looked so tiny in the middle of the full-size ICU bed. The whole left side of her head and her left eye were swollen and bruised, with scratches here and there. Now and then she would stiffen and shake—convulsions probably due to her head injury.

Little Hannah was born on a Saturday night in "Blind Town," the area in Jos where many of the blind people, mostly beggars, live. It's a regular community of its own, with customs, rules, and its own chief. Though Hannah's seventeen-year-old single mother was not blind, she did live there. ...continued
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Cholera: A New Homeland in Africa?
published 01-11-2007

Views : 827

Times marked as favorite : 114


Cholera (Public Health Image Library)"The reported incidence of indigenous cholera in sub-Saharan Africa in 2005 ... was 95 times higher than the reported incidence in Asia ... and 16,600 times higher than the reported incidence in Latin America .... In that same year, the cholera case fatality rate in sub-Saharan Africa (1.8%) was 3 times higher than that in Asia (0.6%); no cholera deaths were reported in Latin America. The persistence or control of cholera in Africa will be a key indicator of global efforts to reach the Millennium Development Goals and of recent commitments by leaders of the G-8 countries to increase development aid to the region."

Cholera: A New Homeland in Africa? Am. J. Trop. Med. Hyg., 77(4), 2007, pp. 705-713. Nov 2007.
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New Digital X-Ray Machine for Evangel
published 26-10-2007

Views : 809

Times marked as favorite : 126


Evangel hospital last week unveiled its brand new digital x-ray machine. For some time we have been struggling with our old machines, and the last one was starting to give images of rather poor quality. The new machine represents our commitment to quality of care and is a big improvement in our ability to diagnose patients. Not only are the images of high quality, but they can be stored and transmitted digitally anywhere in the world. Click on photos for larger view.
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Avian influenza in Africa -- still headed for disaster?
published 23-10-2007

Views : 793

Times marked as favorite : 116


This is a short, sobering article that all of us in Africa should read. Perhaps the pandemic will never develop, but the signs are still worrisome. Maybe there is still time to correct some of the deficiencies in policy and practice that are highlighted in this article.

Avian influenza H5N1 in Africa: an epidemiological twist. The Lancet Infectious Diseases 2007; 7:696-697 DOI:10.1016/S1473-3099(07)70244-X.
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The realities of antiretroviral therapy rollout: a broad look
published 23-10-2007

Views : 786

Times marked as favorite : 104


An entire issue (supplement) of Journal of Infectious Diseases is devoted to a look at the "rollout" or scaling up of antiretroviral treatment in developing countries, mainly South Africa. See the full table of contents for articles including
and ten other articles.

The realities of antiretroviral therapy rollout. J. Infect. Dis. 196 Suppl. 3, December 2007.
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BBC Headline: "HIV treatment 'failing' in Africa." Do you agree?
published 17-10-2007

Views : 793

Times marked as favorite : 109


A BBC news headline reported yesterday, "HIV treatment 'failing' in Africa". The article goes on to say, "More than a third of patients on HIV medication in sub-Saharan Africa die or discontinue their treatment within two years of starting it, a survey shows."

I have not yet read the article, published in PLoS Medicine, but will soon. Meanwhile, here are two questions for you to think about and, if you want, comment below.

  • Is it a "failure" that 61% of patients are alive and continuing treatment after two years in an ART program?
  • The study includes reports published between 2000 and 2007. Do the results take into account any changes in during that time? That is, are programs more or less effective now than they were 10 years ago? Is there enough information to know? Again, I haven't read it yet but it's a good question to consider as you read.

Rosen S, Fox MP, Gill CJ. Patient Retention in Antiretroviral Therapy Programs in Sub-Saharan Africa: A Systematic Review. PLoS Med 4(10): e298. Oct 2007. doi:10.1371/journal.pmed.0040298. Free access.


Keywords : HIV; HIV/AIDS; antiretroviral; ART; ARV; therapy; Africa; adherence; program
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