1. Haloperidol plus promethazine better than haloperidol alone for rapid tranquilization
(Journal Club/Family practice)

... confidence interval 4 to 16; P=0.002). No differences were found after 20 minutes. However, 10 cases of acute dystonia occurred, all in the haloperidol alone group. " Rapid tranquillisat...

2. New reviews on hypertension, atrial fibrillation, acute respiratory distress syndrome, gallstones
(Journal Club/General Review Articles)

BMJ: Clinical Review: Acute respiratory distress syndrome BMJ Clinical Review: Gallstones Lancet Seminar: Essential hypertension. Lancet Review: Management of atrial fibrillation

3. Oral co-amoxiclav alone effective for first episode of pyelonephritis in children
(Journal Club/Pediatrics)

...The guidelines now suggest treatment with oral antibiotics in children aged 3 months and older with with acute pyelonephritis or upper urinary tract infection. ... continuedThe study, carried out in I...

4. Acute HIV infection in first six months of life: case report
(Journal Club/HIV)

A case report of a 6 month old infant with a acute HIV infection probably acquired while breastfeeding during the primary infection in the mother. Symptoms: "Our patient's prolonged viral syndro

5. Cardiac effects of antimalarial drugs: a review
(Journal Club/Malaria)

"Summary "There are consistent differences in cardiovascular state between acute illness in malaria and recovery that prolong the electrocardiographic QT interval and have been misinter

6. Short-term mortality and implementation of ART for critically ill HIV-infected children (S Africa)
(Journal Club/HIV)

...tigation." Despite the perhaps confusing title, the study does not look at the question of the acute use of antiretroviral therapy (i.e, during the illness requiring hospitalization), althou...

7. Ibuprofen superior to paracetamol (acetaminophen) and codeine for musculoskeletal pain in children
(Journal Club/Pediatrics)

...e other 2 groups." A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. Pediatrics. 2007 Mar;119(3):460-7....

8. Avian Influenza ("Bird Flu") H5N1
(FAQs/Health and Illness)

... Sputum production is variable and sometimes bloody. Rapid clinical deterioration: acute respiratory distress often within 4-6 days. Multiorgan dysfunction, may have di...

9. Community-based treatment of severe, acute malnutrition -- a better way?
(Journal Club/Public Health)

...approach promises to be a successful and cost-effective treatment strategy." Management of severe acute malnutrition in children. The Lancet 2006; 368:1992-2000 ...

10. Oral misoprostol successfully prevents postpartum hemorrhage in resource-poor settings
(Journal Club/Public Health)

...by 75%. "Interpretation: Oral misoprostol was associated with significant decreases in the rate of acute postpartum haemorrhage and mean blood loss. The drug's low cost, ease of administration, ...

11. Wait-and-see prescription promising for acute otitis media
(Journal Club/Pediatrics)

...been "yes," while in parts of Europe antibiotics are not used initially for uncomplicated acute otitis media, which generally resolves spontaneously. This study looks at a wait-and-see-...

12. No benefit of frusemide (furosemide) for acute renal failure in adults -- meta-analysis
(Journal Club/Family practice)

"Nine randomised controlled trials totalling 849 patients with or at risk of acute renal failure were included." "Conclusions Frusemide is not associated with any significant clinical

13. Biochemical "liver function tests" (Review, BMJ 2006)
(Journal Club/General Review Articles)

...enzymes produced by the liver) are a common finding in the investigation of patients presenting with non-acute illness and often raise questions about the need for, and timing of, further investigatio...

14. Acute appendicitis (Review in BMJ, 2006)
(Journal Club/General Review Articles)

Acute appendicitis. BMJ 2006;333:530-534. Free via Hinari.

15. Delayed antibiotic prescribing recommended strategy for acute infective conjunctivitis
(Journal Club/Family practice)

"Delayed prescribing of antibiotics is probably the most appropriate strategy for managing acute conjunctivitis in primary care," conclude the authors of this randomized study of adults and

16. IPTp/SP gives added benefit beyond treated bednets in pregnancy
(Journal Club/Malaria)

...g the disease burden one year after implementing a program of intermittent preventive treatment in Koupéla district, Burkina Faso. Am. J. Trop. Med. Hyg., 75(2), 2006, pp. 205-211 ...

17. Should antiretrovirals be started during acute, severe illness?
(Journal Club/HIV)

...t of particular interest is the question of whether to start antiretroviral therapy for patients who are acutely ill. According to the article, there are almost no studies that adress this issue, apar...

18. Atypical organisms causing acute tonsillopharyngitis may cause later lower respiratory tract infect
(Journal Club/Pediatrics)

Evidence for atypical organisms (as above) was sought in children with acute tonsillopharyngitis but without evidence of Streptococcus pyogenes. The children then were randomly assigned to receive eit

19. Parvovirus B19 Infection Contributes to Severe Anemia in Young Children in Papua New Guinea
(Journal Club/Pediatrics)

...t severe anemia. The results were that the severely anemic children were more likely to have evidence of acute parvovirus B19 infection (adjusted odds ratio, 5.61). "Conclusions. B19 infe...

20. Was the study big enough? Two simple rules of 50
(Journal Club/Statistics and Epidemiology)

... you understand the concept of power and sample size determination. Was the study big enough? Two café rules. Evidence-Based Medicine 2006;11:69-70; doi:10.1136/ebm.11.3.69. Full text via Hin...