1. Encouraging news on intermittent preventive therapy in infancy (IPTi) for malaria
(Journal Club/Malaria)

... Purpose of review: This review summarizes recent evidence regarding the efficacy of intermittent preventive treatment with focus on infancy (IPTi) and the rationale behind such a control strategy. ...

2. Epidemiology of congenital malaria in Nigeria: a multi-centre study
(Journal Club/Pediatrics)

... birth. Conclusion Congenital malaria is often asymptomatic, clears spontaneously and may not warrant treatment. However, newborns with unexplained fever and refusal to feed in malaria endemic ...

3. Better first line treatment needed for children with severe pneumonia
(Journal Club/Pediatrics)

...-defined severe or very severe pneumonia. Sixty-eight percent of the children were HIV infected. The empiric treatment used was benzylpenicillin, gentamicin and, for those less than a year old, high-d...

4. Staff supervision and financial incentives improve in-hospital mortality in childhood malaria
(Journal Club/Pediatrics)

...l the staff were retrained in caring for patients with malaria, and all the children received free drugs for treatment. See "read more" for more details and discussion, or read the full arti...

5. Examining once daily gentamicin in the treatment of UTI in infants and children
(Journal Club/Pediatrics)

...les and complete follow-up of participants. Is a once daily dose of gentamicin safe and effective in the treatment of uti in infants and children? Archives of Disease in Childhood 2007;92:823-824;...

6. Practical guide to managing warts and molluscum
(Journal Club/Pediatrics)

This useful article, with plenty of photos, balances the lack of good treatment options with the need to "do something" about these common skin problems. Warts, molluscum and things th

7. Early antiretroviral treatment saves lives in TB/HIV coinfection--Thailand
(Journal Club/HIV)

When should antiretroviral treatment be started in patients with both tuberculosis and HIV infections? There are many considerations including the pill burden, possible drug reactions, drug interactio

8. The realities of antiretroviral therapy rollout: a broad look
(Journal Club/HIV)

...urnal of Infectious Diseases is devoted to a look at the "rollout" or scaling up of antiretroviral treatment in developing countries, mainly South Africa. See the full table of contents for ...

9. The anatomy of a malaria disaster: Modeling malaria epidemics and child mortality
(Journal Club/Malaria)

...ck of community pressure for drug policy change." In other words, people will keep believing in a given treatment long after it is no longer effective, a dangerous situation. We see this with our...

10. Oral Drug Therapy for Multiple Neglected Tropical Diseases
(Journal Club/Public Health)

...alence of hookworm (8.1% to 1.3%), roundworm (28.4% to 0.9%), and whipworm (51.9% to 31.9%). No RCT examined treatment of river blindness or trachoma as part of an intervention to target 2 or more neg...

11. BBC Headline: "HIV treatment 'failing' in Africa." Do you agree?
(Journal Club/HIV)

A BBC news headline reported yesterday, "HIV treatment 'failing' in Africa". The article goes on to say, "More than a third of patients on HIV medication in sub-Saharan Africa die or di

12. "Syndromic management" may be, well, useless (?) for chlamydia and N. gonorrhea in Batswana women
(Journal Club/Public Health)

...egnancy substantially. To diagnose and treat asymptomatic cervical infections, and to reduce the massive overtreatment in the syndromic management, specific diagnostic tests are necessary. Screening f...

13. Zinc and child mortality: what is known?
(Journal Club/Public Health)

...ce, if the upper boundary of the confidence interval includes an important benefit, the possibility that the treatment still might be worthwhile has not been ruled out."  In plain English, t...

14. Pediatric Tuberculosis and HIV/TB Coinfection: Two online, multimedia presentation (free CME :-)
(News/News for Doctors)

... "This slide presentation with streaming audio provides information to strengthen the diagnostic and treatment skills of clinicians working with children with latent TB infection (LTBI) or act...

15. The many benefits of ivermectin??
(Journal Club/Public Health)

...d in the article, have various benefits, the study itself does little to demonstrate those benefits; placebo treatment might have been seen as just as beneficial. Or did I miss something ...? Th...

16. Depression common in elderly Nigerians
(Journal Club/Public Health)

...r 65). Of special note, "there was a mean delay of 5 years from onset of depression to receipt of first treatment." That probably surprises no one, but it certainly shows a glaring gap that ...

17. Control of Neglected Tropical Diseases (NEJM)
(Journal Club/Public Health)

...much morbidity and poverty in the developing world. The article discusses what is currently being done, what treatments are available, and what new efforts are needed to bring these diseases under con...

18. Training Adherence Support Workers
(AIDSLink/Resources)

... learn to interact with patients in clinical, community, and home settings where they provide HIV education, treatment support, and ART adherence counselling. They are also taught to participate in th...

19. Oral co-amoxiclav alone effective for first episode of pyelonephritis in children
(Journal Club/Pediatrics)

...y reported in this week's BMJ found that oral co-amoxiclav was as effective as parenteral ceftriaxone in the treatment of first-episode pyelonephritis in children. The randomized, controlled trial fou...

20. Once daily treatment for HIV infected children
(Journal Club/HIV)

"METHODS. A novel, once-daily dosing regimen of 3 antiretroviral drugs, emtricitabine, didanosine, and efavirenz, was tested in 37 therapy-naive HIV-infected children and adolescents between 3 an