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Home arrow Journal Club arrow By category arrow Malaria arrow Artesunate versus quinine for treatment of severe falciparum malaria (Lancet)

Artesunate versus quinine for treatment of severe falciparum malaria (Lancet) Print E-mail
published 26-09-2005

Views : 366

Times marked as favorite : 39

The Lancet 2005; 366:717-725
DOI:10.1016/S0140-6736(05)67176-0
Open label RCT of IV artesunate vs quinine for severe malaria in three south Asian countries. Mortality in artesunate recipients was 15% (107 of 730) compared with 22% (164 of 731) in quinine recipients. Treatment with artesunate was well tolerated, whereas quinine was associated with hypoglycaemia.

(This article is also reviewed in Evidence Based Medicine, 2006;11:52; doi:10.1136/ebm.11.2.52)

   
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Keywords : malaria, artesunate, quinine, treatment, severe, management, hypoglycemia, SEAQUAMAT

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