ECWA Evangel Hospital, Jos, Nigeria - Co-trimoxazole prophylaxis, ART, and IT bednets each help prevent malaria

ECWA Evangel Hospital, Jos, Nigeria Compassionate Healthcare in the Name of Christ

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Co-trimoxazole prophylaxis, ART, and IT bednets each help prevent malaria

published 12-05-2006

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Observational study in HIV+ subjects, with four sequential phases: no intervention, co-trimoxazole prophylaxis, addition of HAART, and finally the addition of bednets. Each additional intervention was associated with a fall in the rate of malaria infection. The authors discuss the implications, including the suggestion that IT bednets be used more freely in HIV+ patients. Limitations of the observational design are also discussed.

Effect of co-trimoxazole prophylaxis, antiretroviral therapy, and insecticide-treated bednets on the frequency of malaria in HIV-1-infected adults in Uganda. Lancet 367(9518), 15 April 2006.