| published 24-03-2007
|
Views : 903 |
Times marked as favorite : 37 |
This randomized, controlled study allocated 100 children with musculoskeletal injury to receive ibuprofen, paracetamol (acetaminophen) or codeine for pain relief. Ibuprofen (10 mg/kg) was significantly more effective than the other two.
From the abstract:
"Children 6 to 17 years old with pain from a musculoskeletal injury (to extremities, neck, and back) that occurred in the preceding 48 hours before presentation in the emergency department were randomly assigned to receive orally 15 mg/kg acetaminophen, 10 mg/kg ibuprofen, or 1 mg/kg codeine."
"A total of 336 patients were randomly assigned, and 300 were included in the analysis of the primary outcome (100 in the acetaminophen group, 100 in the ibuprofen group, and 100 in the codeine group)." A visual-analog scoring system was used to assess pain.
"Patients in the ibuprofen group had a significantly greater improvement in pain score (mean decrease: 24 mm) than those in the codeine (mean decrease: 11 mm) and acetaminophen (mean decrease: 12 mm) groups at 60 minutes. In addition, at 60 minutes more patients in the ibuprofen group achieved adequate analgesia (as defined by a visual analog scale <30 mm) than the other 2 groups."
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. Pediatrics. 2007 Mar;119(3):460-7.
|
|
|
Readers' Comments  |
|
Average user rating
 (0 vote)
|
|
Add your comment
|
