| published 27-03-2007
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 Two newly reported randomized, controlled trials of male circumcision in Africa, involving nearly 10,000 men, confirm that male circumcision significantly reduces the risk of HIV acquisition. Circumcised men were only half as likely to become as infected as the control group over a two-year period. This is a highly significant and important result: a vaccine that was 50% effective would be considered a huge success. See the studies (click read more) and accompanying review and commentary for the overall implications and where we should go from here.
All the articles below are from The Lancet, Volume 369, Issue 9562 , 24 February 2007-2 March 2007.
Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial.
Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial
Male circumcision and HIV/AIDS: challenges and opportunities. Includes discussion of
- Determining acceptability
- Communicating the benefits of male circumcision
- Defining risk, benefit, and harm reduction
- A framework for a combination prevention strategy
- Funding for social and behavioural research and fighting gender inequality
- Defining the effect of male circumcision on women
- Religious and cultural practices
- When to circumcise
- Male circumcision versus female genital mutilation
- Safety and complications
- Health systems
- The broader context of sexual and reproductive health
- Addressing perceptions of inequitable power relations
- Avoiding branding of men as perpetrators of infection
Male circumcision to cut HIV risk in the general population
Implications, unanswered questions, ethical issues.
Newer approaches to HIV prevention
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