ECWA Evangel Hospital, Jos, Nigeria - Rectal administration of artemisinin antimalarials generally effective--a meta-analysis

ECWA Evangel Hospital, Jos, Nigeria Compassionate Healthcare in the Name of Christ

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Malaria

Rectal administration of artemisinin antimalarials generally effective--a meta-analysis

published 29-07-2007

Times marked as favorite : 46

"Conclusions Available rectal preparations of artemisinin derivatives differ in their pharmacokinetic disposition. Most available evidence pertains to artesunate and artemisinin. Despite marked interindividual variability in bioavailability, rectal preparations appear to have acceptable therapeutic efficacy, including in severe illness." (Emphasis added).

Rectal Administration of Artemisinin Derivatives for the Treatment of Malaria. JAMA. 2007;297:2381-2390.