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Home arrow Journal Club arrow By category arrow Pediatrics arrow Examining once daily gentamicin in the treatment of UTI in infants and children

Examining once daily gentamicin in the treatment of UTI in infants and children Print E-mail
published 25-10-2007

Views : 751

Times marked as favorite : 57

This article not only gives us some answers to the question, "can gentimicin be given once daily in children with UTI?", but it also takes us through the process of how to research and answer the question. A good example to use in teaching.

Clinical bottom line of this, quoted from the article: (OD = once daily)
  • Available evidence supports the efficacy of OD gentamicin in children with UTI. (Grade A)
  • There is limited evidence regarding the safety of OD gentamicin. (Grade B)
  • Issues of nephrotoxicity and ototoxicity require further clarification by well-structured RCTs with larger samples and complete follow-up of participants.
Is a once daily dose of gentamicin safe and effective in the treatment of uti in infants and children? Archives of Disease in Childhood 2007;92:823-824; doi:10.1136/adc.2007.121079.

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Keywords : genticin; gentimicin; daily; once; children; infants; urinary; tract; infection; uti

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