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Home arrow Journal Club arrow By category arrow HIV arrow Breast-Milk Shedding of Drug-Resistant HIV-1 Subtype C in Women Exposed to Single-Dose Nevirapine

Breast-Milk Shedding of Drug-Resistant HIV-1 Subtype C in Women Exposed to Single-Dose Nevirapine Print E-mail
published 05-10-2005

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ImagePlasma and breastmilk (BM) viral titers were obtained from women a median of 8 weeks after single-dose nevirapine. Samples from women with laboratory-diagnosed mastitis had higher viral titers in BM than those without mastitis. In the 20  women with detectable virus in BM, 65% of BM and 50% of plasma RT sequences had NNRTI-resistance mutations, with divergent mutation patterns. The Journal of Infectious Diseases 2005;192:1260-1264
   
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